Active immunization of cattle with killed vaccines prepared from cell-cultured Rinderpest virus.

Active Immunization of Cattle with Killed Vaccines Prepared from Cell Cultured Rinderpest Virus

Immunological responses of mice and cattle to baculovirus-expressed F and H proteins of rinderpest virus: lack of protection in the presence of neutralizing antibody.

Rinderpest is a highly contagious viral disease of ruminants and has greater than 95% morbidity and mortality. The etiological agent, rinderpest virus (RPV), is a member of the family Paramyxoviridae and the genus Morbillivirus. Immune responses to both the hemagglutinin (H) and the fusion (F) antigens of morbilliviruses play an important role in the prevention of infection, and only attenuated...

Recombinant rinderpest vaccines expressing membrane-anchored proteins as genetic markers: evidence of exclusion of marker protein from the virus envelope.

Rinderpest virus (RPV) causes a severe disease of cattle resulting in serious economic losses in parts of the developing world. Effective control and elimination of this disease require a genetically marked rinderpest vaccine that allows serological differentiation between animals that have been vaccinated against rinderpest and those which have recovered from natural infection. We have constru...

The immunization of cattle against rinderpest in eighteenth-century Europe.

Rinderpest is caused by a morbillivirus closely related to the measles and canine distemper viruses. The pathology and symptomatology of the three diseases are very similar,1 but in terms of mortality, rinderpest is by far the most lethal; in European cattle the death rate often exceeds 80 per cent. The disease was eradicated in Europe over a hundred years ago, but in the eighteenth century an ...

Oral immunization of cattle with hemagglutinin protein of rinderpest virus expressed in transgenic peanut induces specific immune responses.

Rinderpest is an acute, highly contagious often fatal disease of large and small ruminants, both domestic and wild. Global eradication of rinderpest needs a robust, safe and cost-effective vaccine. The causative agent, rinderpest virus (RPV) is an important member of the genus Morbillivirus in the Paramyxoviridae family. We have generated transgenic peanut (Arachis hypogea L.) plants expressing...